学位取得者・一覧（2015年以降）

山田　健介 (2021年3月)	「Siglec-7は転移性結腸直腸癌に対するワクチン療法の効果予測バイオマーカーである」
藤本　拓也 (2021年3月)	「Cathepsin Bは膵臓stem like cellsに高発現し、治療切除後の予後と関連している」
中島　千代 (2020年9月)	「大腸癌の新規予後マーカーである血清LOX-1」
桑原　太一 (2020年3月)	「切除可能結腸直腸癌に対する強力な予後予測マーカーとしての腫瘍内浸潤CD4 およびFOXP3陽性T細胞」
中島　正夫 (2020年3月)	「PD-1に対する一本鎖抗体を分泌するCAR-T細胞はCAR-T細胞のみならず、内因性の腫瘍抗原特異的リンパ球のアポトーシスを抑制し固形がんに対して高い治療効果を有する」
西山　光郎 (2018年9月)	「肝癌由来細胞株から誘導した癌幹細胞様細胞における転移能および上皮間葉系転換に関する解析」
亀井　滝士 (2018年6月：論文博士)	「胃癌切除患者におけるULBP1とNKG2Dの発現レベルは全生存期間に影響を与える」
田中　宏典 (2018年3月)	「miR-125b-1とmiR-378aは大腸癌ワクチン療法の効果予測バイオマーカーである。」
長島　由紀子 (2018年3月：論文博士)	「Lentinula edodes mycelia抽出物が乳癌術後補助化学療法のQOLと免疫能改善におよぼす影響―無作為化試験の結果」
小長井　文乃 (2017年11月：論文博士)	「NKG2Dリガンドの発現と担癌マウスモデルにおけるPSKの抗腫瘍効果との相関」
松井　洋人 (2017年9月)	「膵癌根治切除後のゲムシタビン・養子免疫併用補助療法」
北原　正博 (2017年3月)	「結腸直腸癌患者の血漿中のcell-free DNA integrityを測定することによる免疫療法の有効性の予測」
来嶋　大樹 (2017年3月)	「血漿中のMicroRNA-6826と6875は転移性大腸癌に対するワクチン療法の効果を予測する有用で非侵襲的なバイオマーカーである。」
松隈　聰 (2017年3月)	「Calreticulinは膵癌幹細胞様細胞に高発現している。」
井上　由佳 (2015年3月)	「切除不能進行再発大腸癌におけるセツキシマブ療法に対する治療効果予測因子としてのFcγRとEGFRの遺伝子多型の有用性についての検討」
徳光　幸生 (2015年3月)	「肝細胞癌根治切除術後の新たな予後予測ステージングシステムの開発」
橋本　憲輝 (2015年3月)	「脱分化型肝細胞癌由来細胞株から誘導した癌幹細胞様Sphere細胞は抗癌剤耐性を有する」
前田　祥成 (2015年3月)	「HCV関連HCCに対するheat-shock protein 70 messenger RNA導入樹状細胞療法を用いた第１相臨床試験」
渡邊　裕策 (2015年3月)	「神経刺激因子を含む幹細胞培地は膵癌幹細胞を誘導する」
新藤 芳太郎 (2015年3月)	「マウス皮下腫瘍モデルに対する抗4-1BB抗体／抗PD-1抗体を用いた癌免疫療法」
中尾　光宏 (2015年3月)	「小腸伸長術に小腸再生医療を応用した小腸再生伸長術」

英文論文・一覧（2015年以降）

2021年

Fujimoto T, Tsunedomi R, Matsukuma S, Yoshimura K, Oga A, Fujiwara N, Fujiwara Y, Matsui H, Shindo Y, Tokumitsu Y, Suzuki N, Kobayashi S, Hazama S, Eguchi H, Nagano H. Cathepsin B is highly expressed in pancreatic cancer stem-like cells and is associated with patients’ surgical outcomes. Oncol Lett. 2021 Jan; 21(1): 30.

Yamada K, Hazama S, Suzuki N, Xu M, Nakagami Y, Fujiwara N, Tsunedomi R, Yoshida S, Tomochika S, Matsukuma S, Matsui H, Tokumitsu Y, Kanekiyo S, Shindo Y, Watanabe Y, Iida M, Takeda S, Ioka T, Ueno T, Ogihara H, Hamamoto Y, Hoshii Y, Kawano H, Fujita T, Kawakami Y, Nagano H. Siglec-7 is a predictive biomarker for the efficacy of cancer vaccination against metastatic colorectal cancer. Oncol Lett. 2021 Jan; 21(1): 10.

Fujimoto Y, Suehiro Y, Kaino S, Suenaga S, Tsuyama T, Matsui H, Higaki S, Fujii I, Suzuki C, Hoshida T, Matsumoto T, Takami T, Nagano H, Sakaida I, Yamasaki T. Combination of CA19-9 and Blood Free-Circulating Methylated RUNX3 May Be Useful to Diagnose Stage I Pancreatic Cancer. Oncology. 2021 Jan 13: 1-6.

Amo-Shiinoki K, Tanabe K, Hoshii Y, Matsui H, Harano R, Fukuda T, Takeuchi T, Bouchi R, Takagi T, Hatanaka M, Takeda K, Okuya S, Nishimura W, Kudo A, Tanaka S, Tanabe M, Akashi T, Yamada T, Ogawa Y, Ikeda E, Nagano H, Tanizawa Y. Islet cell dedifferentiation is a pathologic mechanism of long-standing progression of type 2 diabetes. JCI Insight. 2021 Jan 11; 6(1): e143791.

Shinozaki K, Yamada T, Nasu J, Matsumoto T, Yuasa Y, Shiraishi T, Nagano H, Moriyama I, Fujiwara T, Miguchi M, Yoshida R, Nozaka K, Tanioka H, Nagasaka T, Kurisu Y, Kobayashi M, Tsuchihashi K, Inukai M, Kikuchi T, Nishina T. A phase II study of FOLFOXIRI plus bevacizumab as initial chemotherapy for patients with untreated metastatic colorectal cancer: TRICC1414 (BeTRI). Int J Clin Oncol. 2021 Feb; 26(2): 399-408.

Saito A, Toyoda H, Kobayashi M, Koiwa Y, Fujii H, Fujita K, Maeda A, Kaneoka Y, Hazama S, Nagano H, Mirza AH, Graf HP, Cosatto E, Murakami Y, Kuroda M. Prediction of early recurrence of hepatocellular carcinoma after resection using digital pathology images assessed by machine learning. Mod Pathol. 2021 Feb; 34(2): 417-425.

Kang CM, Suh KS, Yi NJ, Hong TH, Park SJ, Ahn KS, Hayashi H, Choi SB, Jeong CY, Takahara T, Shiozaki S, Roh YH, Yu HC, Fukumoto T, Matsuyama R, Naoki U, Hashida K, Seo HI, Okabayashi T, Kitajima T, Satoi S, Nagano H, Kim H, Taira K, Kubo S, Choi DW. Should Lymph Nodes Be Retrieved in Patients with Intrahepatic Cholangiocarcinoma? A Collaborative Korea-Japan Study. Cancers (Basel). 2021 Jan 25; 13(3): 445.

Takaichi S, Tomimaru Y, Kobayashi S, Takeda Y, Nakahira S, Tsujie M, Yukawa M, Shimizu J, Murakami M, Miyamoto A, Asaoka T, Sakai K, Morimoto O, Tori M, Yamamoto T, Fukuchi N, Nagano H, Doki Y, Eguchi H; Clinical Study Group of Osaka University, Hepato-Biliary-Pancreatic Group. Drainage after laparoscopic liver surgery in the CSGO-HBP-004 study: propensity score-matched analysis. Br J Surg. 2021 Mar 12; 108(2): e57-e58.

Shindo Y, Kobayashi S, Wada H, Tokumitsu Y, Matsukuma S, Matsui H, Nakajima M, Yoshida S, Iida M, Suzuki N, Takeda S, Hoshii Y, Eguchi H, Nagano H. Short and long-term outcomes of simultaneous hepatic artery resection and reconstruction for perihilar cholangiocarcinoma. Gastrointest Tumors. Gastrointest Tumors. 2021 Jan; 8(1): 25-32.

Matsui H, Hazama S, Nakajima M, Xu M, Matsukuma S, Tokumitsu Y, Shindo Y, Tomochika S, Yoshida S, Iida M, Suzuki N, Takeda S, Yoshino S, Ueno T, Oka M, Nagano H. Novel adjuvant dendritic cell therapy with transfection of heat-shock protein 70 messenger RNA for patients with hepatocellular carcinoma: a phase I/II prospective randomized controlled clinical trial. Cancer Immunol Immunother. 2021 Apr; 70(4): 945-957 and 959.

Fujiwara Y, Tsunedomi R, Yoshimura K, Matsukuma S, Fujiwara N, Nishiyama M, Kanekiyo S, Matsui H, Shindo Y, Tokumitsu Y, Yoshida S, Iida M, Suzuki N, Takeda S, Ioka T, Hazama S, Nagano H. Pancreatic Cancer Stem-Like Cells with high Calreticulin expression associated with immune surveillance. Pancreas. 2021 Mar 1; 50(3): 405-413.

Kuhara K, Kitagawa T, Baron B, Tokuda K, Sakamoto K, Nagano H, Nakamura K, Kobayashi M, Nagayasu H, Kuramitsu Y. Proteomic analysis of hepatocellular carcinoma tissues with encapsulation shows up-regulation of leucine aminopeptidase 3 and phosphoenolpyruvate arboxykinase 2. Cancer Genomics Proteomics. 2021 May-Jun; 18(3): 307-316.

Suzuki N, Yoshida S, Tomochika S, Nakagami Y, Shindo Y, Tokumitsu Y, Iida M, Takeda S, Hazama S, Ueno T, Nagano H. Determining protective characteristics and risk factors for the development of anastomotic leakage after low anterior resection for rectal cancer. Surg Today. 2021 May; 51(5): 713-720.

Marubashi S、Nagano H. Laparoscopic living-donor hepatectomy: Review of its current status. Ann Gastroenterol Surg. 2021 Mar 2; 5(4): 484-493.

Miyasaka Y, Ohtsuka T, Eguchi S, Inomata M, Nishihara K, Shinchi H, Okuda K, Baba H, Nagano H, Ueki T, Noshiro H, Nakamura M; Kyushu study group of treatment for pancreatobiliary cancer. Neoadjuvant Chemotherapy with Gemcitabine Plus Nab-Paclitaxel Regimen for Borderline Resectable Pancreatic Cancer with Arterial Involvement: A Prospective Multicenter Single-Arm Phase II Study Protocol. Int J Surg Protoc. 2021 Apr 26; 25(1): 55-60.

Yamagata H, Kobayashi A, Tsunedomi R, Seki T, Kobayashi M, Hagiwara K, Chen C, Uchida S, Okada G, Fuchikami M, Kamishikiryo T, Iga JI, Numata S, Kinoshita M, Kato TA, Hashimoto R, Nagano H, Okamoto Y, Ueno S, Ohmori T, Nakagawa S. Optimized protocol for the extraction of RNA and DNA from frozen whole blood sample stored in a single EDTA tube. Sci Rep. 2021 Aug 23; 11(1): 17075.

Tomochika S, Suzuki N, Yoshida S, Fujii T, Tokumitsu Y, Shindo Y, Iida M, Takeda S, Hazama S, Nagano H. Laparoscopic sutureless rectopexy using a fixation device for complete rectal prolapse. Surg Laparosc Endosc Percutan Tech. 2021 May 21;　31(5):　608-612.

Tanaka Y, Takeuchi H, Nakashima Y, Nagano H, Ueno T, Tomizuka K, Morita S, Emi Y, Hamai Y, Hihara J, Saeki H, Oki E, Kunisaki C, Otsuji E, Baba H, Matsubara H, Maehara Y, Kitagawa Y, Yoshida K. Effects of an elemental diet to reduce adverse events in patients with esophageal cancer receiving docetaxel/cisplatin/5-fluorouracil: a phase III randomized controlled trial-EPOC 2 (JFMC49-1601-C5). ESMO Open. 2021 Oct; 6(5): 100277.

Matsukuma S, Tokumitsu Y, Nakagami Y, Shindo Y, Matsui H, Nakajima M, Iida M, Suzuki N, Takeda S, Nagano H. Laparoscopic resection reduces superficial surgical site infection in liver surgery. Surg Endosc. 2021 Jan 4. doi: 10.1007/s00464-020-08233-9. Online ahead of print.

Shindo Y, Tokumitsu Y, Matsukuma S, Matsui H, Nakajima M, Suzuki N, Takeda S, Hoshii Y, Nagano H. Hepatic artery resection and reconstruction using the right gastroepiploic artery during pancreaticoduodenectomy in advanced pancreatic cancer. Langenbecks Arch Surg. 2021 Apr 13. doi: 10.1007/s00423-021-02120-0. Online ahead of print.

Kim HS, Song W, Choo W, Lee S, Han Y, Bassi C, Salvia R, Marchegiani G, Wolfgang CL, He J, Blair AB, Kluger MD, Su GH, Kim SC, Song KB, Yamamoto M, Hatori T, Yang CY, Yamaue H, Hirono S, Satoi S, Fujii T, Hirano S, Lou W, Hashimoto Y, Shimizu Y, Del Chiaro M, Valente R, Lohr M, Choi DW, Choi SH, Heo JS, Motoi F, Matsumoto I, Lee WJ, Kang CM, Shyr YM, Wang SE, Han HS, Yoon YS, Besselink MG, van Huijgevoort NCM, Sho M, Nagano H, Kim SG, Honda G, Yang Y, Yu HC, Do Yang J, Chung JC, Nagakawa Y, Seo HI, Lee S, Kim H, Kwon W, Park T, Jang JY. Development, Validation, and Comparison of a Nomogram Based on Radiologic Findings for Predicting Malignancy in Intraductal Papillary Mucinous Neoplasms of the Pancreas: An International Multicenter Study. J Hepatobiliary Pancreat Sci. 2021 Apr 2. doi: 10.1002/jhbp.962. Online ahead of print.

Kubo M, Gotoh K, Kobayashi S, Iwagami Y, Yamada D, Tomimaru Y, Akita H, Noda T, Marubashi S, Nagano H, Dono K, Doki Y, Eguchi H. Modified Cavoportal Hemitransposition for Severe Portal Vein Thrombosis Contributed to Long-term Survival After Deceased Donor Liver Transplantation-Insight into Portal Modulation for Improving Survival: A Case Report. Transplant Proc. 2021 Jul 9: S0041-1345 (21) 00445-0. doi: 10.1016/j.transproceed.2021.06.025. Online ahead of print.

Takayama W, Endo A, Murata K, Hoshino K, Kim S, Shinozaki H, Harada K, Nagano H, Hagiwara M, Tsuchihashi A, Shimada N, Kitamura N, Kuramoto S, Otomo Y. The impact of blood type on the mortality of patients with severe abdominal trauma: a multicenter observational study. Sci Rep. 2021 Aug 9; 11(1): 16147.

Elbadawy M, Hayashi K, Ayame H, Ishihara Y, Abugomaa A, Shibutani M, Hayashi SM, Hazama S, Takenouchi H, Nakajima M, Tsunedomi R, Suzuki N, Nagano H, Shinohara Y, Kaneda M, Yamawaki H, Usui T, Sasaki K. Anti-cancer activity of amorphous curcumin preparation in patient-derived colorectal cancer organoids. Biomed Pharmacother. 2021 Aug 16; 142: 112043.

Ikeda N, Yamamoto H, Taketomi A, Hibi T, Ono M, Niikura N, Sugitani I, Isozumi U, Miyata H, Nagano H, Unno M, Kitagawa Y, Mori M. The impact of COVID-19 on surgical procedures in Japan: an analysis of data of the National Clinical Database. Surg Today. 2021 Nov 16:1-14. doi: 10.1007/s00595-021-02406-2. Online ahead of print.

2020年

Eguchi H, Kawamoto K, Tsujie M, Yukawa M, Kubota M, Asaoka T, Takeda Y, Noda T, Shimizu J, Nagano H, Doki Y, Mori M. A prospective, multi-center Phase I study of postoperative enoxaparin treatment in patients undergoing curative hepatobiliary-pancreatic surgery for malignancies. Dig Surg. 2020; 37(1): 81-86.

Elbadawy M, Yamanaka M, Goto Y, Hayashi K, Tsunedomi R, Hazama S, Nagano H, Yoshida T, Shibutani M, Ichikawa R, Nakahara J, Omatsu T, Mizutani T, Katayama Y, Shinohara Y, Abugomaa A, Kaneda M, Yamawaki H, Usui T, Sasaki K. Efficacy of primary liver organoid culture from different stages of non-alcoholic steatohepatitis (NASH) mouse model. Biomaterials. 2020 Jan 27; 237: 119823.

Nagano H. The time has come for Japanese surgeons to work in English. Ann Gastroenterol Surg. 2020 Jan 30; 4(1): 5.

Kotoh Y, Suehiro Y, Saeki I, Hoshida T, Maeda M, Iwamoto T, Matsumoto T, Hidaka I, Ishikawa T, Takami T, Higaki S, Fujii I, Suzuki C, Shindo Y, Tokumitsu Y, Nagano H, Sakaida I, Yamasaki T. Novel Liquid Biopsy Test Based on a Sensitive Methylated SEPT9 Assay for Diagnosing Hepatocellular Carcinoma. Hepatol Commun. 2020 Jan 2; 4(3): 461-470.

Sakon M, Kobayashi S, Wada H, Eguchi H, Marubashi S, Takahashi H, Akita H, Gotoh K, Yamada D, Asukai K, Hasegawa S, Ohue M, Yano M, Nagano H. “Logic-based medicine” is more feasible than “evidence-based medicine” in the local treatment for hepatocellular carcinoma. Oncology. 2020; 98(5): 259-266.

Tomimaru Y, Eguchi H, Iwagami Y, Akita H, Noda T, Gotoh K, Kobayashi S, Nagano H, Mori M, Doki Y. Preoperative chemoradiotherapy using gemcitabine for pancreatic ductal adenocarcinoma in patients with impaired renal function. Cancer Chemother Pharmacol. 2020 Mar; 85(3): 537-545.

Matsukuma S, Eguchi H, Wada H, Noda T, Shindo Y, Tokumitsu Y, Matsui H, Takahashi H, Kobayashi S, Nagano H. Liver resection with thrombectomy improves the survival of patients with hepatocellular carcinoma and tumor thrombi in the inferior vena cava or right atrium. BJS Open. 2020 Apr; 4(2): 241-251.

Tokumitsu Y, Shindo Y, Matsui H, Matsukuma S, Nakajima M, Yoshida S, Iida M, Suzuki N, Takeda S, Nagano H. Laparoscopic total biopsy for suspected gallbladder cancer: A case series. Health Sci Rep. 2020 Apr 20; 3(2): e156.

Kim DS, Kim BW, Hatano E, Hwang S, Hasegawa K, Kudo A, Ariizumi S, Kaibori M, Fukumoto T, Baba H, Kim SH, Kubo S, Kim JM, Ahn KS, Choi SB, Jeong CY, Shima Y, Nagano H, Yamasaki O, Yu HC, Han DH, Seo HI, Park IY, Yang KS, Yamamoto M, Wang HJ. Surgical Outcomes of Hepatocellular Carcinoma with Bile Duct Tumor Thrombus: A Korea-Japan Multicenter Study, Ann Surg. 2020 May; 271(5): 913-921.

Suehiro Y, Hashimoto S, Goto A, Yamaoka Y, Yamamoto N, Suzuki N, Higaki S, Fujii I, Suzuki C, Matsumoto T, Hoshida T, Koga M, Tsutsumi T, Lim LA, Matsubara Y, Takami T, Yoshida S, Hazama S, Yotsuyanagi H, Nagano H, Sakaida I, Yamasaki T. Fecal DNA Testing of TWIST1 Methylation identifies patients with advanced colorectal adenoma missed by fecal immunochemical test for hemoglobin. Clin Transl Gastroenterol. 2020 Jun; 11(6): e00176.

Yamashita YI, Aishima S, Nakao Y, Yoshizumi T, Nagano H, Kuroki T, Takami Y, Ide T, Ohta M, Takatsuki M, Nanashima A, Nanashima A, Ishis F, Kitahara K, Iino S, Beppu T, Baba H, Eguchi S. Clinicopathological characteristics of combined hepatocellular-cholangiocarcinoma from the viewpoint of patient prognosis after hepatic resection: High rate of early recurrence and its predictors. Hepatol Res. 2020 July; 50(7): 863-870.

Mori M, Ikeda N, Taketomi A, Asahi Y, Takesue T, Orimo T, Ono M, Kuwayama T, Nakamura S, Yamada Y, Kuroda T, Yuzawa K, Hibi T, Nagano H, Unno M, Kitagawa Y. COVID-19: Clinical issues from Japan Surgical Society. Surge Today. 2020 July; 50(7): 794-808.

Iida M, Takeda S, Nakagami Y, Kanekiyo S, Nakashima C, Nishiyama M, Yoshida S, Suzuki N, Yoshino S, Nagano H. The effect of the visceral fat area on the predictive accuracy of C-reactive protein for infectious complications after laparoscopy-assisted gastrectomy. Ann Gastroenterol Surg. 2020 Mar 31; 4(4): 386-395.

Nakashima-Nakasuga C, Hazama S, Suzuki N, Nakagami Y, Xu M, Yoshida S, Tomochika S, Fujiwara N, Matsukuma S, Matsui H, Tokumitsu Y, Kanekiyo S, Shindo Y, Maeda N, Tsunedomi R, Iida M, Takeda S, Yoshino S, Ueno T, Hamamoto Y, Ogihara H, Hoshii Y, Nagano H. Serum LOX-1 is a novel prognostic biomarker of colorectal cancer. Int J Clin Oncol. 2020 Jul; 25(7): 1308-1317.

Nakajima M, Hazama S, Tamada K, Udaka K, Kouki Y, Uematsu T, Arima H, Saito A, Miyakawa T, Doi S, Matsui H, Shindo Y, Matsukuma S, Kanekiyo S, Tokumitsu Y, Tomochika S, Iida M, Yoshida S, Nakagami Y, Suzuki N, Takeda S, Yamamoto S, Yoshino S, Ueno T, Nagano H. A phase I study of multi-HLA-binding peptides derived from heat shock protein 70/glypican-3 and a novel combination adjuvant of hLAG-3Ig and Poly-ICLC for patients with metastatic gastrointestinal cancers: YNP01 trial. Cancer Immunol Immunother. 2020 Aug; 69(8): 1651-1662.

Maeda H, Okada KI, Fujii T, Oba MS, Kawai M, Hirono S, Kodera Y, Sho M, Akahori T, Shimizu Y, Ambo Y, Kondo N, Murakami Y, Ohuchida J, Eguchi H, Nagano H, Sakamoto J, Yamaue H. No Significant effect of Daikenchuto (TJ-100) on peritoneal IL-9 and IFN-γ levels after pancreaticoduodenectomy. Clin Exp Gastroenterol. 2020 Oct 19; 13: 461-466.

Imaoka H, Ikeda M, Maehara K, Umemoto K, Ozaka M, Kobayashi S, Terashima T, Inoue H, Sakaguchi C, Tsuji K, Shioji K, Okamura K, Kawamoto Y, Suzuki R, Shirakawa H, Nagano H, Ueno M, Morizane C, Furuse J. Clinical outcomes of chemotherapy in patients with undifferentiated carcinoma of the pancreas: a retrospective multicenter cohort study. BMC Cancer. 2020 Oct 1; 20(1): 946.

Eguchi H, Iwagami Y, Matsushita K, Tomimaru Y, Akita H, Noda T, Gotoh K, Kobayashi S, Nagano H, Mori M, Doki Y. Randomized clinical trial of pancreaticogastrostomy versus pancreaticojejunostomy regarding incidence of delayed gastric emptying after pancreaticoduodenectomy. Langenbecks Arch Surg. 2020 Nov; 405(7): 921-928.

Mlecnik B, Bifulco C, Bindea G, Marliot F, Lugli A, Lee JJ, Zlobec I, Rau TT, Berger MD, Nagtegaal ID, Vink-Börger E, Hartmann A, Geppert C, Kolwelter J, Merkel S, Grützmann R, Van den Eynde M, Jouret-Mourin A, Kartheuser A, Léonard D, Remue C, Wang JY, Bavi P, Roehrl MHA, Ohashi PS, Nguyen LT, Han S, MacGregor HL, Hafezi-Bakhtiari S, Wouters BG, Masucci GV, Andersson EK, Zavadova E, Vocka M, Spacek J, Petruzelka L, Konopasek B, Dundr P, Skalova H, Nemejcova K, Botti G, Tatangelo F, Delrio P, Ciliberto G, Maio M, Laghi L, Grizzi F, Fredriksen T, Buttard B, Lafontaine L, Bruni D, Lanzi A, El Sissy C, Haicheur N, Kirilovsky A, Berger A, Lagorce C, Paustian C, Ballesteros-Merino C, Dijkstra J, van de Water C, van Lent-van Vliet S, Knijn N, Muşină AM, Scripcariu DV, Popivanova B, Xu M, Fujita T, Hazama S, Suzuki N, Nagano H, Okuno K, Torigoe T, Sato N, Furuhata T, Takemasa I, Itoh K, Patel PS, Vora HH, Shah B, Patel JB, Rajvik KN, Pandya SJ, Shukla SN, Wang Y, Zhang G, Kawakami Y, Marincola FM, Ascierto PA, Fox BA, Pagès F, Galon J. Multicenter International Society for Immunotherapy of Cancer Study of the Consensus Immunoscore for the Prediction of Survival and Response to Chemotherapy in Stage III Colon Cancer. J Clin Oncol. 2020 Nov 1; 38(31): 3638-3651.

Nakajima M, Kobayashi S, Wada H, Tomokuni A, Takahashi H, Noda T, Matsui H, Matsukuma S, Kanekiyo S, Shindo Y, Tokumitsu Y, Nakagami Y, Suzuki N, Takeda S, Eguchi H, Nagano H. Viral elimination is essential for improving surgical outcomes of hepatitis C virus-related hepatocellular carcinoma: multicenter retrospective analysis. Ann Gastroenterol Surg. 2020 Jul 23; 4(6): 710-720.

Kang JS, Lee C, Song W, Choo W, Lee S, Lee S, Han Y, Bassi C, Salvia R, Marchegiani G, Wolfgang CL, He J, Blair AB, Kluger MD, Su GH, Kim SC, Song KB, Yamamoto M, Higuchi R, Hatori T, Yang CY, Yamaue H, Hirono S, Satoi S, Fujii T, Hirano S, Lou W, Hashimoto Y, Shimizu Y, Del Chiaro M, Valente R, Lohr M, Choi DW, Choi SH, Heo JS, Motoi F, Matsumoto I, Lee WJ, Kang CM, Shyr YM, Wang SE, Han HS, Yoon YS, Besselink MG, van Huijgevoort NCM, Sho M, Nagano H, Kim SG, Honda G, Yang Y, Yu HC, Do Yang J, Chung JC, Nagakawa Y, Seo HI, Choi YJ, Byun Y, Kim H, Kwon W, Park T, Jang JY. Risk prediction for malignant intraductal papillary mucinous neoplasm of the pancreas: logistic regression versus machine learning. Sci Rep. 2020 Nov 18; 10(1): 20140. doi: 10.1038/s41598-020-76974-7.

Matsukuma S, Nagano H, Kobayashi S, Wada H, Seo S, Tsugawa D, Okuyama H, Iida K, Ohmura Y, Takeda Y, Miyamoto A, Nakashima S, Yamada T, Ajiki T, Tsuji A, Yoshimura K, Eguchi H, Hatano E, Ioka T; Kansai Hepato-Biliary Oncology (KHBO) Group. The impact of peritoneal lavage cytology in biliary tract cancer (KHBO1701): Kansai Hepato-Biliary Oncology Group. Cancer Rep (Hoboken). 2020 Dec 6: e1323.

Tsunedomi R, Yoshimura K, Suzuki N, Hazama S, Nagano H. Clinical implication of cancer stem cells in digestive cancers: acquisition of stemness and prognostic impact. Surg Today. 2020 Dec;50(12):1560-1577.

Takeda S, Iida M, Kanekiyo S, Nishiyama M, Tokumitsu Y, Shindo Y, Yoshida S, Suzuki N, Yoshino S, Nagano H. Efficacy of intraoperative recurrent laryngeal neuromonitoring during surgery for esophageal cancer. Ann Gastroenterol Surg. 2020 Sep 17; 5(1): 83-92.

2019年

Tomimaru Y, Eguchi H, Wada H, Doki Y, Mori M, Nagano H. Surgical outcomes of liver resection combined with inferior vena cava resection and reconstruction with artificial vascular graft. Dig Surg. 2019; 36(6): 502-508.

Kanekiyo S, Takeda S, Iida M, Nishiyama M, Kitahara M, Shindo Y, Tokumitsu Y, Tomochika S, Tsunedomi R, Suzuki N, Abe T, Yoshino S, Hazama S, Ueno T, Nagano H. Efficacy of perioperative immunonutrition in esophageal cancer patients undergoing esophagectomy. Nutrition. 2019 Mar; 59: 96-102.

Kurahara H, Shinchi H, Ohtsuka T, Miyasaka Y, Matsunaga T, Noshiro H, Adachi T, Eguchi S, Imamura N, Nanashima A, Sakamoto K, Nagano H, Ohta M, Inomata M, Chikamoto A, Baba H, Watanabe Y, Nishihara K, Yasunaga M, Okuda K, Natsugoe S, Nakamura M. Significance of neoadjuvant therapy for borderline resectable pancreatic cancer: a multicenter retrospective study. Langenbecks Arch Surg. 2019 Mar; 404(2): 167-174.

Morooka Y, Umeshita K, Taketomi A, Ken S, Yoshizumi T, Yamamoto M, Shimamura T, Oshita A, Ohdan H, Kawagishi N, Hagiwara K, Eguchi H, Nagano H. Long-term Donor Quality of Life after Living Donor Liver Transplantation in Japan. Clin Transplant. 2019 May 9:e13584.

Suehiro K, Yamamoto S, Honda S, Morikage N, Harada E, Takemoto Y, Nagano H, Hamano K. Perioperative variations in indices derived from noninvasive assessments to detect postmastectomy lymphedema. J Vasc Surg Venous Lymphat Disord. 2019 Jul;7(4):562-569. doi: 10.1016/j.jvsv.2019.02.012.

Matsuda T, Miyauchi E, Hsu YW, Nagayama S, Kiyotani K, Zewde M, Park JH, Kato T, Harada M, Matsui S, Ueno M, Fukuda K, Suzuki N, Hazama S, Nagano H, Takeuchi H, Vigneswaran WT, Kitagawa Y, Nakamura Y. TCR sequencing analysis of cancer tissues and tumor draining lymph nodes in colorectal cancer patients. Oncoimmunology. 2019 Mar 22;8(6):e1588085.

Katsuda M, Miyazawa M, Ojima T, Katanuma A, Hakamada K, Sudo K, Asahara S, Endo I, Ueno M, Hara K, Yamada S, Fujii T, Satoi S, Ioka T, Ohira M, Akahori T, Kitano M, Nagano H, Furukawa M, Adachi T, Yamaue H. A double-blind randomized comparative clinical trial to evaluate the safety and efficacy of dendritic cell vaccine loaded with WT1 peptides (TLP0-001) in combination with S-1 in patients with advanced pancreatic cancer refractory to standard chemotherapy. Trials. 2019 Apr 27;20(1):242.

Kobayashi S, Nagano H, Tomokuni A, Gotoh K, Sakai D, Hatano E, Seo S, Terajima H, Uchida Y, Ajiki T, Satake H, Kamei K, Tohyama T, Hirose T, Ikai I, Morita S, Ioka T; Kansai Hepato-Biliary Oncology (KHBO) Group. A Prospective, Randomized Phase II Study of Adjuvant Gemcitabine Versus S-1 After Major Hepatectomy for Biliary Tract Cancer (KHBO 1208): Kansai Hepato-Biliary Oncology Group. Ann Surg. 2019 Aug; 270(2): 230-237.

Matsukuma S, Tokumitsu Y, Shindo Y, Matsui H, Nagano H. Essential updates to the surgical treatment of biliary tract cancer. Ann Gastroenterol Surg. 2019 May 22; 3(4): 378-389.

Matsui H, Hazama S, Tamada K, Udaka K, Nishimura Y, Miyakawa T, Doi S, Nakajima M, Kanekiyo S, Tokumitsu Y, Shindo Y, Tomochika S, Yoshida S, Iida M, Suzuki N, Takeda S, Yamamoto S, Yoshino S, Ueno T, Nagano H. Identification of a promiscuous epitope peptide derived from HSP70. J Immunotherapy. 2019 Sep;42(7):244-250.

Shindo Y, Hazama S, Tsunedomi R, Suzuki N, Nagano H. Biomarkers in immunotherapy for cancer. Cancers (Basel). 2019 Aug 22;11(9). pii: E1223.

Tokumitsu Y, Shindo Y, Matsui H, Matsukuma S, Nakajima M, Suzuki N, Takeda S, Wada H, Kobayashi S, Eguchi H, Ueno T, Nagano H. Utility of scoring systems combining the product of tumor number and size with liver function for predicting the prognosis of patients with hepatocellular carcinoma after hepatectomy. Oncol Lett. 2019 Oct; 18(4): 3903-3913.

Nakajima M, Sakoda Y, Adachi K, Nagano H, Tamada K. Improved survival of CAR-T and tumor-specific T cells caused by anti-PD-1 scFv-producing CAR-T cells. Cancer Sci. 2019 Oct; 110(10): 3079-3088.

Kuwahara T, Hazama S, Suzuki N, Yoshida S, Tomochika S, Nakagami Y, Matsui H, Shindo Y, Kanekiyo S, Tokumitsu Y, Iida M, Tsunedomi R, Takeda S, Yoshino S, Okayama N, Suehiro Y, Yamasaki T, Fijita T, Kawakami Y, Ueno T, Nagano H. Intratumoural-infiltrating CD4+ and FOXP3+ T Cells as strong positive predictive markers for the prognosis of resectable colorectal cancer. Br J Cancer. 2019 Nov; 121(11): 983-984..

Oga T, Yamashita Y, Soda M, Kojima S, Ueno T, Kawazu M, Suzuki N, Nagano H, Hazama S, Izumiya M, Koike K, Mano H. Genomic profiles of colorectal carcinoma with liver metastases and newly identified fusion genes. Cancer Sci. 2019 Sep; 110(9): 2973-2981.

Suzuki N, Hazama S, Nagasaka T, Tanioka H, Iwamoto Y, Negoro Y, Yamauchi M, Kobayashi M, Okuda H, Fujishima N, Nishimura T, Yamanaka N, Toyota K, Mori Y, Nakagami Y, Shimokawa M, Nagano H, Okajima M.　Multicenter phase II study of biweekly XELIRI plus bevacizumab as second-line therapy in patients with metastatic colorectal cancer (JSWOG-C3 study). Int J Clin Oncol. 2019 Oct; 24(10): 1223-1230.

Eguchi H, Takeda Y, Takahashi H, Nakahira S, Kashiwazaki M, Shimizu J, Sakai D, Isohashi F, Nagano H, Mori M, Doki Y. A Prospective, Open-Label, Multicenter Phase 2 Trial of Neoadjuvant Therapy Using Full-Dose Gemcitabine and S-1 Concurrent with Radiation for Resectable Pancreatic Ductal Adenocarcinoma. Ann Surg Oncol. 2019 Dec; 26(13): 4498-4505.

Kokudo N, Takemura N, Hasegawa K, Takayama T, Kubo S, Shimada M, Nagano H, Hatano E, Izumi N, Kaneko S, Kudo M, Iijima H, Genda T, Tateishi R, Torimura T, Igaki H, Kobayashi S, Sakurai H, Murakami T, Watadani T, Matsuyama Y. Clinical Practice Guidelines for Hepatocellular Carcinoma: The Japan Society of Hepatology 2017 (4th JSH-HCC Guidelines) a 2019 update. Hepatol Res. 2019 Oct; 49(10): 1109-1113.

Kudo M, Ueshima K, Chiba Y, Ogasawara S, Obi S, Izumi N, Aikata H, Nagano H, Hatano E, Sasaki Y, Hino K, Kumada T, Yamamoto K, Imai Y, Iwadou S, Ogawa C, Okusaka T, Kanai F, Arai Y. Objective Response by mRECIST Is an Independent Prognostic Factor for Overall Survival in Hepatocellular Carcinoma Treated with Sorafenib in the SILIUS Trial. Liver Cancer. 2019 Nov; 8(6): 505-519.

Shuto T, Nishikawa J, Shimokuri K, Yanagi A, Takagi T, Takagi F, Miura O, Iida M, Nagano H, Takemoto Y, Harada E, Suehiro Y, Yamasaki T, Okamoto T, Sakaida I. Establishment of a Screening Method for Epstein-Barr Virus-Associated Gastric Carcinoma by Droplet Digital PCR. Microorganisms. 2019 Nov 29; 7(12). pii: E628.

Maeda H, Hazama S, Iwamoto S, Oba K, Tsunedomi R, Okayama N, Suehiro Y, Yamasaki T, Nakagami Y, Suzuki N, Nagano H, Sakamoto J, Mishima H, Nagata N. Association between polymorphisms in EGFR and tumor response during cetuximab and oxaliplatin-based combination therapy in metastatic colorectal cancer: Analysis of data from two clinical trials. Oncol Lett. 2019 Nov;18(5):4555-4562.

2018年

Yamanaka C, Wada H, Eguchi H, Hatano H, Gotoh K, Noda T, Yamada D, Asaoka T, Kawamoto K, Nagano H, Doki Y, Mori M. Clinical significance of CD13 and epithelial mesenchymal transition (EMT) markers in hepatocellular carcinoma. Jpn J Clin Oncol. 2018 Jan 1;48(1):52-60.

Wada H, Eguchi H, Nagano H, Kubo S, Nakai T, Kaibori M, Hayashi M, Takemura S, Tanaka S, Nakata Y, Matsui K, Ishizaki M, Hirokawa F, Komeda K, Uchiyama K, Kon M, Doki Y, Mori M. Perioperative allogenic blood transfusion is a poor prognostic factor after hepatocellular carcinoma surgery: a multi-center analysis. Surg Today. 2018 Jan; 48(1): 73-79.

Suehiro Y, Zhang Y, Hashimoto S, Takami T, Higaki S, Shindo Y, Suzuki N, Hazama S, Oka M, Nagano H, Sakaida I, Yamasaki T. Highly sensitive faecal DNA testing of TWIST1 methylation in combination with faecal immunochemical test for haemoglobin is a promising marker for detection of colorectal neoplasia. Ann Clin Biochem. 2018 Jan; 55(1): 59-68.

Kamei R, Yoshimura K, Yoshino S, Inoue M, Asao T, Fuse M, Wada S, Kuramasu A, Furuya-Kondo T, Oga A, Iizuka N, Suzuki N, Maeda N, Watanabe Y, Matsukuma S, Iida M, Takeda S, Ueno T, Yamamoto N, Fukagawa T, Katai H, Sasaki H, Hazama S, Oka M, Nagano H. Expression levels of UL16 binding protein 1 and natural killer group 2 member D affect overall survival in patients with gastric cancer following gastrectomy. Oncol Lett. 2018 Jan; 15(1): 747-754.

Nakajima M, Yoshino S, Kanekiyo S, Maeda N, Sakamoto K, Tsunedomi R, Suzuki N, Takeda S, Yamamoto S, Hazama S, Hoshii Y, Oga A, Itoh H, Ueno T, Nagano H. High secreted protein acidic and rich in cysteine expression in peritumoral fibroblasts predicts better prognosis in patients with resectable gastric cancer. Oncol Lett. 2018 Jan; 15(1): 803-812.

Kobayashi S, Fukui K, Takeda Y, Nakahira S, Tsujie M, Shimizu J, Miyamoto A, Eguchi H, Nagano H, Doki Y, Mori M. Short-term outcomes of open liver resection and laparoscopic liver resection: Secondary analysis of data from a multicenter prospective study (CSGO-HBP-004). Ann Gastroenterol Surg. 2018; 2(1): 87 -94.

Enjoji S, Yabe R, Tsuji S, Yoshimura K, Kawasaki H, Sakurai M, Sakai Y, Takenouchi H, Yoshino S, Hazama S, Nagano H, Oshima H, Oshima M, Vitek MP, Matsuura T, Hippo Y, Usui T, Ohama T, Sato K. Stemness is Enhanced in Gastric Cancer by a SET/PP2A/E2F1 Axis. Mol Cancer Res. 2018 Mar; 16(3): 554-563.

Yanagimoto H, Toyokawa H, Sakai D, Wada H, Satoi S, Yamamoto T, Nagano H, Toyoda M, Ajiki T, Satake H, Tsuji A, Miyamoto A, Tsujie M, Takemura S, Yanagihara K, Ioka T. A phase I study for adjuvant chemotherapy of gemcitabine plus S-1 in patients with biliary tract cancer undergoing curative resection without major hepatectomy (KHBO1202).　 Cancer Chemother Pharmacol. 2018 Mar; 81(3): 461-468.

Yamamoto Y, Tsunedomi R, Fujita Y, Otori T, Ohba M, Kawai Y, Hirata H, Matsumoto H, Haginaka J, Suzuki S, Dahiya R, Hamamoto Y, Matsuyama K, Hazama S, Nagano H, Matsuyama H. Pharmacogenetics-based area-under-curve model can predict efficacy and adverse events from axitinib in individual patients with advanced renal cell carcinoma. Oncotarget. 2018 Mar 30; 9(24): 17160-17170.

Nishioka M, Suehiro Y, Sakai K, Matsumoto T, Okayama N, Mizuno H, Ueno K, Suzuki N, Hashimoto S, Takami T, Hazama S, Nagano H, Sakaida I, Yamasaki T. TROY is a promising prognostic biomarker in patients with colorectal cancer. Oncol Lett. 2018 Apr; 15(4): 5989-5994.

Tokumitsu Y, Sakamoto K, Matsui Y, Matsukuma S, Tokuhisa Y, Tamesa T, Yoshino S, Hazama S, Maeda Y, Sakata K, Wada H, Eguchi, H, Ogihara H, Fujita Y, Hamamoto Y, Iizuka N, Ueno T, Nagano H. A new prognostic model for hepatocellular carcinoma recurrence after curative hepatectomy. Oncol Lett. 2018 Apr; 15(4): 4411-4422.

Kanekiyo S, Takeda S, Tsutsui M, Nishiyama M, Kitahara M, Shindo Y, Tokumitsu Y, Tomochika S, Tokuhisa Y, Iida M, Sakamoto K, Suzuki N, Yamamoto S, Yoshino S, Hazama S, Ueno T, Nagano H. Low invasiveness of thoracoscopic esophagectomy in the prone position for esophageal cancer: a propensity score-matched comparison of operative approaches between thoracoscopic and open esophagectomy. Surg Endosc. 2018 Apr; 32(4): 1945-1953.

Nishiyama M, Tsunedomi R, Yoshimura K, Hashimoto N, Matsukuma S, Ogihara H, Kanekiyo S, Iida M, Sakamoto K, Suzuki N, Takeda S, Yamamoto S, Yoshino S, Ueno T, Hamamoto Y, Hazama S, Nagano H. Metastatic ability and the epithelial-mesenchymal transition in induced cancer stem-like hepatoma cells. Cancer Sci. 2018 Apr; 109(4): 1101-1109.

Yamaoka Y, Suehiro Y, Hashimoto S, Hoshida T, Fujimoto M, Watanabe M, Imanaga D, Sakai K, Matsumoto T, Nishioka M, Takami T, Suzuki N, Hazama S, Nagano H, Sakaida I, Yamasaki T. Fusobacterium nucleatum as a prognostic marker of colorectal cancer in a Japanese population. J Gastroenterol. 2018 Apr; 53(4): 517-524.

Kanekiyo S, Hazama S, Takenouchi H, Nakajima M, Shindo Y, Matsui H, Tokumitsu Y, Tomochika S, Tsunedomi R, Tokuhisa Y, Iida M, Sakamoto K, Suzuki N, Takeda S, Yamamoto S, Yoshino S, Okuno K, Udaka K, Kawakami Y, Matsueda S, Ito K, Nagano H. IgG response to MHC class I epitope peptides is a quantitative predictive biomarker in the early course of treatment of colorectal cancer using therapeutic peptides. Oncol Rep. 2018 May; 39(5): 2385-2392.

Usui T, Sakurai M, Umata K, Elbadawy M, Ohama T, Yamawaki H, Hazama S, Takenouchi H, Nakajima M, Tsunedomi R, Suzuki N, Nagano H, Sato K, Kaneda M, Sasaki K. Hedgehog Signals Mediate Anti-Cancer Drug Resistance in Three-Dimensional Primary Colorectal Cancer Organoid Culture. Int J Mol Sci. 2018 Apr 6;19(4).

Kudo M, Ueshima K, Yokosuka O, Ogasawara S, Obi S, Izumi N, Aikata H, Nagano H, Hatano E, Sasaki Y, Hino K, Kumada T, Yamamoto K, Imai Y, Iwadou S, Ogawa C, Okusaka T, Kanai F, Akazawa K, Yoshimura K, Johnson P, Arai Y; SILIUS study group. Sorafenib plus low-dose cisplatin and fluorouracil hepatic arterial infusion chemotherapy versus sorafenib alone in patients with advanced hepatocellular carcinoma (SILIUS): a randomised, open label, phase 3 trial. Lancet Gastroenterol Hepatol. 2018 Jun; 3(6): 424-432.

Tomimaru Y, Eguchi H, Wada H, Doki Y, Mori M, Nagano H. Liver resection combined with inferior vena cava resection and reconstruction using artificial vascular graft: A literature review. Ann Gastroenterol Surg. 2018 Apr 15; 2(3): 182-186.

Pagès F, Mlecnik B, Marliot F, Bindea G, Ou FS, Bifulco C, Lugli A, Zlobec I, Rau TT, Berger MD, Nagtegaal ID, Vink-Börger E, Hartmann A, Geppert C, Kolwelter J, Merkel S, Grützmann R, Van den Eynde M, Jouret-Mourin A, Kartheuser A, Léonard D, Remue C, Wang JY, Bavi P, Roehrl MHA, Ohashi PS, Nguyen LT, Han S, MacGregor HL, Hafezi-Bakhtiari S, Wouters BG, Masucci GV, Andersson EK, Zavadova E, Vocka M, Spacek J, Petruzelka L, Konopasek B, Dundr P, Skalova H, Nemejcova K, Botti G, Tatangelo F, Delrio P, Ciliberto G, Maio M, Laghi L, Grizzi F, Fredriksen T, Buttard B, Angelova M, Vasaturo A, Maby P, Church SE, Angell HK, Lafontaine L, Bruni D, El Sissy C, Haicheur N, Kirilovsky A, Berger A, Lagorce C, Meyers JP, Paustian C, Feng Z, Ballesteros-Merino C, Dijkstra J, van de Water C, van Lent-van Vliet S, Knijn N, Mușină AM, Scripcariu DV, Popivanova B, Xu M, Fujita T, Hazama S, Suzuki N, Nagano H, Okuno K, Torigoe T, Sato N, Furuhata T, Takemasa I, Itoh K, Patel PS, Vora HH, Shah B, Patel JB, Rajvik KN, Pandya SJ, Shukla SN, Wang Y, Zhang G, Kawakami Y, Marincola FM, Ascierto PA, Sargent DJ, Fox BA, Galon J. International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study. Lancet. 2018 May 26; 391(10135): 2128-2139.

Hazama S, Tamada K, Yamaguchi Y, Kawakami Y, Nagano H. Current status of immunotherapy against gastrointestinal cancers and its biomarkers: Perspective for precision immunotherapy. Ann Gastroenterol Surg. 2018 Jun 22; 2(4): 289-303.

Noguchi K, Konno M, Eguchi H, Kawamoto K, Mukai R, Nishida N, Koseki J, Wada H, Akita H, Satoh T, Marubashi S, Nagano H, Doki Y, Mori M, Ishii H. c-Met affects gemcitabine resistance during carcinogenesis in a mouse model of pancreatic cancer. Oncol Lett. 2018 Aug; 16(2): 1892-1898.

Yamada T, Gotoh K, Marubashi S, Asaoka T, Miyamoto A, Kobayashi S, Eguchi H, Shimizu J, Kim Y, Tsujie M, Noda T, Yokoyama S, Takeda Y, Mori M, Doki Y, Nagano H. Comparison of adverse events and outcomes between patients with and without drain insertion after hepatectomy: a propensity score-matched, multicenter, prospective observational cohort study in Japan (CSGO-HBP-001). World J Surg. 2018 Aug; 42(8): 2561-2569.

Iida M, Hazama S, Tsunedomi R, Tanaka H, Takenouchi H, Kanekiyo S, Tokumitsu Y, Tomochika S, Tokuhisa Y, Sakamoto K, Suzuki N, Takeda S, Ueno T, Yamamaoto S, Yoshino S, Fujita K, Kuroda M, Naganao H. Overexpression of miR-221 and miR-222 in the cancer stroma is associated with malignant potential in colorectal cancer. Oncol Rep. 2018 July; 40(3): 1621-1631.

Nagano H, Obi S, Hatano E, Kaneko S, Kanai F, Omata M, Tsuji A, Itamoto T, Yamamoto K, Tanaka M, Kubo S, Hirata K, Nakamura H, Tomimaru Y, Yamanaka T, Kojima S, Monden M. A multicenter, randomized, controlled trial of S-1 monotherapy versus S-1 and interferon-α combination therapy for hepatocellular carcinoma with extrahepatic metastases. Hepatol Res. 2018 Aug; 48(9): 717-726.

Sakamoto K, Nagano H. Outcomes of surgery for hepatocellular carcinoma with tumor thrombus in the inferior vena cava or right atrium. Surg Today. 2018 Sep; 48(9): 819-824.

Matsukuma S, Sakamoto K, Tokuhisa Y, Tokumitsu Y, Matsui H, Kanekiyo S, Tomochika S, Iida M, Suzuki N, Takeda S, Ueno T, Wada H, Kobayashi S, Saeki I, Eguchi H, Sakon M, Sakaida I, Nagano H. Outcomes after liver resection for multinodular Barcelona Clinic Liver Cancer-B hepatocellular carcinoma. Oncol Lett. Oncol Lett. 2018 Nov; 16(5): 6383-6392.

Maeda H, Okada KI, Fujii T, Oba MS, Kawai M, Hirono S, Kodera Y, Sho M, Akahori T, Shimizu Y, Ambo Y, Kondo N, Murakami Y, Ohuchida J, Eguchi H, Nagano H, Sakamoto J, Yamaue H. Transition of serum cytokines following pancreaticoduodenectomy: A subsidiary study of JAPAN-PD. Oncol Lett. 2018 Nov; 16(5): 6847-6853.

Matsui H, Hazama S, Shindo Y, Nagano H. Combined treatment of advanced pancreatic cancer using novel vaccine and traditional therapies. Expert Rev Anticancer Ther. 2018 Dec; 18(12): 1205-1217.

Watanabe K, Yamamoto S, Sakaguti S, Isayama K, Oka M, Nagano H, Mizukami Y. A novel somatic mutation of SIN3A detected in breast cancer by whole-exome sequencing enhances cell proliferation through ERα expression. Sci Rep. 2018 Oct 30; 8(1): 16000.

Fujita Y, Kozawa J, Iwahashi H, Yoneda S, Uno S, Eguchi H, Nagano H, Imagawa A, Shimomura I. Human Pancreatic Alpha- to Beta-Cell Area Ratio Increases After Type 2 Diabetes Onset. J Diabetes Investig. 2018 Nov; 9(6): 1270-1282.

Iwamoto S, Maeda H, Hazama S, Oba K, Okayama N, Suehiro Y, Yamasaki T, Suzuki N, Nagano H, Sakamoto J, Mishima H, Nagata N. Efficacy of CapeOX plus Cetuximab Treatment as a First-Line Therapy for Patients with Extended RAS/BRAF/PIK3CA Wild-Type Advanced or Metastatic Colorectal Cancer. J Cancer. 2018 Oct 18; 9(22): 4092-4098.

Watanabe K, Yamamoto S, Sakaguti S, Isayama K, Oka M, Nagano H, Mizukami Y. A novel somatic mutation of SIN3A detected in breast cancer by whole-exome sequencing enhances cell proliferation through ERα expression. Sci Rep. 2018 Oct 30;8(1):16000.

Nishida S, Ishikawa T, Egawa S, Koido S, Yanagimoto H, Ishii J, Kanno Y, Kokura S, Yasuda H, Oba MS, Sato M, Morimoto S, Fujiki F, Eguchi H, Nagano H, Kumanogoh A, Unno M, Kon M, Shimada H, Ito K, Homma S, Oka Y, Morita S, Sugiyama H. Combination gemcitabine and WT1 peptide vaccination improves progression-free survival in advanced pancreatic ductal adenocarcinoma: A phase II randomized study. Cancer Immunol Res. 2018 Mar; 6(3): 320-331.

2017年

Kijima T, Hazama S, Tsunedomi R, Tanaka H, Takenouchi H, Kanekiyo S, Inoue Y, Nakashima M, Iida M, Sakamoto K, Suzuki N, Takeda S, Ueno T, Yamamoto S, Yoshino S, Okuno K, Nagano H. MicroRNA-6826 and -6875 in plasma are valuable non invasive biomarkers that predict the efficacy of vaccine treatment against metastatic colorectal cancer. Oncol Rep. 2017 Jan; 37(1): 23-30.

Shindo Y, Hazama S, Suzuki N, Iguchi H, Uesugi K, Tanaka H, Aruga A, Hatori T, Ishizaki H, Umeda Y, Fujiwara T, Ikemoto T, Shimada M, Yoshimatsu K, Takenouchi H, Matsui H, Kanekiyo S, Iida M, Koki Y, Arima H, Furukawa H, Ueno T, Yoshino S, Fujita T, Kawakami Y, Nakamura Y, Oka M, Nagano H. Predictive biomarkers for the efficacy of peptide vaccine treatment: based on the results of a phase II study on advanced pancreatic cancer. J Exp Clin Cancer Res. 2017 Feb 28; 36(1): 36.

Takada Y, Kaido T, Shirabe K, Nagano H, Egawa H, Sugawara Y, Taketomi A, Takahara T, Wakabayashi G, Nakanishi C, Kawagishi N, Kenjo A, Gotoh M, Toyoki Y, Hakamada K, Ohtsuka M, Akamatsu N, Kokudo N, Takeda K, Endo I, Takamura H, Okajima H, Wada H, Kubo S, Kuramitsu K, Ku Y, Ishiyama K, Ohdan H, Ito E, Maehara Y, Honda M, Inomata Y, Furukawa H, Uemoto S, Yamaue H, Miyazaki M, Takada T; LTx-PET study group of the Japanese Society of Hepato-Biliary-Pancreatic Surgery, the Japanese Liver Transplantation Society. Significance of preoperative fluorodeoxyglucose-positron emission tomography in prediction of tumor recurrence after liver transplantation for hepatocellular carcinoma patients: A Japanese multicenter study. J Hepatobiliary Pancreat Sci. 2017 Jan; 24(1): 49-57.

Suzuki N, Hazama S, Iguchi H, Uesugi K, Tanaka H, Hirakawa K, Aruga A, Hatori T, Ishizaki H, Umeda Y, Fujiwara T, Ikemoto T, Shimada M, Yoshimatsu K, Shimizu R, Hayashi H, Sakata K, Takenouchi H, Matsui H, Shindo Y, Iida M, Koki Y, Arima H, Furukawa H, Ueno T, Yoshino S, Nakamura Y, Oka M, Nagano H. A phase ΙI clinical trial of peptide cocktail therapy for patients with advanced pancreatic cancer: VENUS-PC study. Cancer Sci. 2017 Jan; 108(1): 73-80.

Inoue Y, Hazama S, Suzuki N, Tokumitsu Y, Kanekiyo S, Tomochika S, Tsunedomi R, Tokuhisa Y, Iida M, Sakamoto K, Takeda S, Ueno T, Yoshino S, Nagano H. Cetuximab strongly enhances immune cell infiltration into liver metastatic sites in colorectal cancer. Cancer Sci. 2017 Mar; 108(3): 455-460.

Ueno T, Iida M, Yoshino S, Takeda S, Kubota H, Higashida M, Oka Y, Tsuruta A, Matsumoto H, Nagano H. East Versus West: Differences in Surgical Management in Asia Compared with Europe and North America. Surg Clin North Am. 2017 Apr; 97(2): 453-466.

Nakajima M, Ueno T, Suzuki N, Matsui H, Shindo Y, Sakamoto K, Tokuhisa Y, Tokumitsu Y, Takeda S, Yoshino S, Hazama S, Nagano H. Novel Indications for Surgical Resection of Metachronous Lung Metastases From Pancreatic Cancer After Curative Resection. J Clin Gastroenterol. 2017; 51(5): e34–e38

Sakamoto K, Takeda S, Kanekiyo S, Nishiyama M, Kitahara M, Ueno T, Yamamoto S, Yoshino S, Hazama S, Okayama N, Nagano H. Association of tumor necrosis factor-α polymorphism with chemotherapy-induced oral mucositis in patients with esophageal cancer. Mol Clin Oncol. 2017 Jan; 6(1): 125-129.

Suehiro Y, Sakai K, Nishioka M, Hashimoto S, Takami T, Higaki S, Shindo Y, Hazama S, Oka M, Nagano H, Sakaida I, Yamasaki T. Highly sensitive stool DNA testing of Fusobacterium nucleatum as a marker for detection of colorectal tumours in a Japanese population. Ann Clin Biochem. 2017 Jan; 54(1): 86-91.

Shindo Y, Hazama S, Nakanmura Y, Inoue Y, Kanekiyo S, Suzuki N, Takenouchi H, Tsunedomi R, Nakajima M, Ueno T, Takeda S, Yoshino S, Okuno K, Fujita Y, Hamamoto Y, Kawakami Y, Oka M, Nagano H. miR-196b, miR-378a and miR-486 are predictive biomarkers for the efficacy of vaccine treatment in colorectal cancer. Oncology Letters 2017; 14: 1355-1362.

Tsunedomi R, Hazama S, Okayama N, Oka M, Nagano H. Rapid and sensitive detection of UGT1A1 polymorphisms associated with irinotecan toxicity by a novel DNA microarray. Cancer Sci. 2017 Jul;108(7):1504-1509.

Konagai A, Yoshimura K, Hazama S, Yamamoto N, Aoki K, Ueno T, Fujioka M, Iijima H, Kato M, Uchida M, Wada T, Inoue M, Asao T, Fuse M, Wada S, Kuramasu A, Kamei R, Takeda S, Yamamoto S, Yoshino S, Oka M, Nagano H. Correlation Between NKG2DL Expression and Antitumor Effect of Protein-bound Polysaccharide-K in Tumor-bearing Mouse Models. Anticancer Res. 2017 Aug; 37(8): 4093-4101.

Sakamoto K, Nagano H. Surgical treatment for advanced hepatocellular carcinoma with portal vein tumor thrombus. Hepatol Res. 2017 Sep; 47(10): 957-962.

Matsui H, Hazama S, Sakamoto K, Shindo Y, Kanekiyo S, Nakashima M, Matsukuma S, Tokuhisa Y, Iida M, Suzuki N, Yoshimura K, Takeda S, Ueno T, Yoshino S, Oka M, Nagano H. Post-Operative Adjuvant Therapy for Resectable Pancreatic Cancer with Gemcitabine and Adoptive Immunotherapy. Pancreas. 2017 2017 Sep; 46(8): 994-1002.

Nagashima Y, Yoshino S, Yamamoto S, Maeda N, Azumi T, Komoike Y, Okuno K, Iwasa T, Tsurutani J, Nakagawa K, Oka M, Nagano H. Lentinula edodes mycelia extract plus adjuvant chemotherapy for breast cancer patients: Results of a randomized study on host quality of life and immune function improvement. Mol Clin Oncol. 2017 Sep; 7(3): 359-366.

Egawa M, Yoshida Y, Ogura S, Kurahashi T, Kizu T, Furuta K, Kamada Y, Chatani N, Hamano M, Kiso S, Hikita H, Tatsumi T, Eguchi H, Nagano H, Doki Y, Mori M, Takehara T. Increased FoxM1 expression is associated with clinicopathological features and confers a poor prognosis in human hepatocellular carcinoma. Hepatol Res. 2017 Oct; 47(11): 1196-1205.

Furukawa K, Tanemura M, Miyoshi E, Eguchi H, Nagano H, Matsunami K, Nagaoka S, Yamada D, Asaoka T, Noda T, Wada H, Kawamoto K, Goto K, Taniyama K, Mori M, Doki Y. A practical approach to pancreatic cancer immunotherapy using resected tumor lysate vaccines processed to express α-gal epitopes. PLoS One. 2017 Oct 27; 12(10): e0184901.

Tanaka H, Hazama S, Iida M, Tsunedomi R, Takenouchi H, Nakajima M, Tokumitsu Y, Kanekiyo S, Shindo Y, Tomochika S, Tokuhisa Y, Sakamoto K, Suzuki N, Takeda S, Yamamoto S, Yoshino S, Ueno T, Hamamoto Y, Fujita Y, Tanaka H, Tahara K, Shimizu R, Okuno K, Fujita K, Kuroda M, Nakamura Y, Nagano H. miR-125b-1 and miR-378a are predictive biomarkers for the efficacy of vaccine treatment against colorectal cancer. Cancer Sci. 2017 Nov; 108(11): 2229-2238.

Yamamoto S, Maeda N, Nagashima Y, Kubo H, Sato Y, Matsui H, Inoue Y, Shindo Y, Kanekiyo S, Sakamoto K, Suzuki N, Takeda S, Ueno T, Yoshino S, Hazama S, Oka M, Nagano H. A phase II, multicenter, single-arm study of tri-weekly low-dose nanoparticle albumin-bound paclitaxel chemotherapy for patients with metastatic or recurrent breast cancer. Breast Cancer. 2017 Nov; 24(6): 783-789.

Jang JY, Park T, Lee S, Kim Y, Lee SY, Kim SW, Kim SC, Song KB, Yamamoto M, Hatori T, Hirono S, Satoi S, Fujii T, Hirano S, Hashimoto Y, Shimizu Y, Choi DW, Choi SH, Heo JS, Motoi F, Matsumoto I, Lee WJ, Kang CM, Han HS, Yoon YS, Sho M, Nagano H, Honda G, Kim SG, Yu HC, Chung JC, Nagakawa Y, Seo HI, Yamaue H. Proposed Nomogram Predicting the Individual Risk of Malignancy in the Patients with Branch Duct Type Intraductal Papillary Mucinous Neoplasms of the Pancreas. Ann Surg. 2017 Dec; 266(6): 1062-1068.

2016年

Hasegawa S, Nagano H, Konno M, Eguchi H, Tomokuni A, Tomimaru Y, Asaoka T, Wada H, Hama N, Kawamoto K, Marubashi S, Nishida N, Koseki J, Mori M, Doki Y, Ishii H. A crucial epithelial to mesenchymal transition regulator, Sox4/Ezh2 axis is closely related to the clinical outcome in pancreatic cancer patients. Int J Oncol. 2016 Jan; 48(1): 145-152.

Hasegawa S, Eguchi H, Tomokuni A, Tomimaru Y, Asaoka T, Wada H, Hama N, Kawamoto K, Kobayashi S, Marubashi S, Konno M, Ishii H, Mori M, Doki Y, Nagano H. Pre-treatment neutrophil to lymphocyte ratio as a predictive marker for pathological response to preoperative chemoradiotherapy in pancreatic cancer. Oncology Letters. 2016 Feb; 11(2): 1560-1566.

Kawai M, Hirono S, Okada KI, Sho M, Nakajima Y, Eguchi H, Nagano H, Ikoma H, Morimura R, Takeda Y, Nakahira S, Suzumura K, Fujimoto J, Yamaue H. Randomized Controlled Trial of Pancreaticojejunostomy versus Stapler Closure of the Pancreatic Stump During Distal Pancreatectomy to Reduce Pancreatic Fistula. Ann Surg. 2016 Jul; 264(1): 180-187.

Kobayashi S, Takeda Y, Nakahira S, Tsujie M, Shimizu J, Miyamoto A, Eguchi H, Nagano H, Doki Y, Mori M. Fibrin Sealant with Polyglycolic Acid Felt vs Fibrinogen-Based Collagen Fleece at the Liver Cut Surface for Prevention of Postoperative Bile Leakage and Hemorrhage: A Prospective, Randomized, Controlled Study. J Am Coll Surg. 2016 Jan; 222(1): 59-64.

Marubashi S, Nagano H, Eguchi H, Wada H, Asaoka T, Tomimaru Y, Tomokuni A, Umeshita K, Doki Y, Mori M. Minimum graft size calculated from pre-operative recipient status in living donor liver transplantation. Liver Transpl. 2016 May; 22(5): 599-606.

Tomimaru Y, Eguchi H, Gotoh K, Kawamoto K, Wada H, Asaoka T, Noda T, Yamada D, Ogawa H, Umeshita K, Nagano H, Doki Y, Mori M. Platelet count is more useful for predicting posthepatectomy liver failure at surgery for hepatocellular carcinoma than indocyanine green clearance test. J Surg Oncol. 2016 Apr; 113(5): 565-569.

Kajihara J, Tomimaru Y, Eguchi H, Yamada D, Wada H, Tomokuni A, Asaoka T, Kawamoto K, Marubashi S, Nagano H, Umeshita K, Doki Y, Mori M. The Clinical Impact of Transcatheter Arterial Chemoembolization (TACE)-Induced c-Met Upregulation on TACE Refractoriness in Hepatocellular Carcinoma. Dig Dis Sci. 2016 Jun; 61(6): 1572-1581.

Sakamoto T, Kobayashi S, Yamada D, Nagano H, Tomokuni A, Tomimaru Y, Noda T, Gotoh K, Asaoka T, Wada H, Kawamoto K, Marubashi S, Eguchi H, Doki Y, Mori M. A Histone Deacetylase Inhibitor Suppresses Epithelial-Mesenchymal Transition and Attenuates Chemoresistance in Biliary Tract Cancer. PLoS One. 2016 Jan 4; 11(1): e0145985.

Okada KI, Kawai M, Hirono S, Fujii T, Kodera Y, Sho M, Nakajima Y, Satoi S, Kwon AH, Shimizu Y, Ambo Y, Kondo N, Murakami Y, Ohuchida J, Eguchi H, Nagano H, Oba MS, Morita S, Sakamoto J, Yamaue H; JAPAN-PD Investigators. Evaluation of the efficacy of daikenchuto (TJ -100) for the prevention of paralytic ileus after pancreaticoduodenectomy: A multicenter, double-blind, randomized, placebo-controlled trial. Surgery. 2016 May; 159(5): 1333-1341.

Ueda M, Kamada Y, Takamatsu S, Shimomura M, Maekawa T, Sobajima T, Fujii H, Nakayama K, Nishino K, Yamada M, Kobayashi Y, Kumada T, Ito T, Eguchi H, Nagano H, Miyoshi E. Specific increase in serum core-fucosylated haptoglobin in patients with chronic pancreatitis. Pancreatology. 2016 Mar-Apr;16(2):238-243.

Maekawa T, Kamada Y, Ebisutani Y, Ueda M, Hata T, Kawamoto K, Takamatsu S, Mizutani K, Shimomura M, Sobajima T, Fujii H, Nakayama K, Nishino K, Yamada M, Kumada T, Ito T, Eguchi H, Nagano H, Miyoshi E. Serum Mac-2 binding protein is a novel biomarker for chronic pancreatitis. World J Gastroenterol. 2016 May 7; 22(17): 4403-4410.

Kanekiyo S, Takeda S, Nakajima M, Nishiyama M, Kitahara M, Shindou Y, Michihisa I, Abe T, Yoshino S, Hazama S, Nagano H. Efficacy and Safety of Biweekly Docetaxel in Combination with Nedaplatin as Second-line Chemotherapy for Unresectable or Recurrent Esophageal Cancer. Anticancer Res. 2016 Apr; 36(4):1923-1927.

Kano Y, Iguchi T, Matsui H, Adachi K, Sakoda Y, Miyakawa T, Doi S, Hazama S, Nagano H, Ueyama Y, Tamada K. Combined adjuvants of poly(I:C) plus LAG-3-Ig improve antitumor effects of tumor-specific T cells, preventing their exhaustion. Cancer Sci. 2016 Apr; 107(4): 398-406.

Ueno M, Nakai T, Hayashi M, Hirokawa F, Nagano H, Wada H, Kaibori M, Matsui K, Tanaka S, Yamaue H, Kubo S. Survival outcome of salvage hepatectomy in patients with local, recurrent hepatocellular carcinoma who underwent radiofrequency ablation as their first treatment. Surgery. 2016 Sep;160(3):661-670.

Wada H, Eguchi H, Noda T, Ogawa H, Yamada D, Tomimaru Y, Tomokuni A, Asaoka T, Kawamoto K, Gotoh K, Marubashi S, Umeshita K, Nagano H, Doki Y, Mori M. Selection criteria for hepatic resection in intermediate-stage (BCLC stage B) multiple hepatocellular carcinoma. Surgery. 2016 Nov; 160(5): 1227-1235.

Kaibori M, Nitta H, Hayashi M, Takemura S, Nagano H, Matsui K, Ikoma H, Nakai T, Yasunaga M, Kido M, Aoki T, Rikiyama T, Sano K, Kudo A, Katagiri S, Otsuka Y, Kuroki T, Nomi T, Yano K, Endo I, Ueno M, Kanazawa A, Terajima H, Ko S, Honda G, Seyama Y, Sunagawa H, Aibara T. Questionnaire survey on work motivations of gastrointestinal and hepatobiliary pancreatic surgeons enrolled in a Japanese national interdisciplinary program. Questionnaire survey on work motivations of gastrointestinal and hepatobiliary pancreatic surgeons enrolled in a Japanese national interdisciplinary program. J Hepatobiliary Pancreat Sci. 2016 Nov; 23(11): 697-702.

Akita H, Ritchie SA, Takemasa I, Eguchi H, Pastural E, Jin W, Yamazaki Y, Goodenowe DB, Nagano H, Monden M, Mori M, Doki Y. Serum Metabolite Profiling for the Detection of Pancreatic Cancer: Results of a Large Independent Validation Study. Pancreas 2016 Nov; 45(10): 1418-1423.

Matsukuma S, Yoshimura K, Ueno T, Oga A, Inoue M, Watanabe Y, Kuramasu A, Fuse M, Tsunedomi R, Nagaoka S, Eguchi H, Matsui H, Shindo Y, Maeda N, Tokuhisa Y, Kawano R, Furuya-Kondo T, Itoh H, Yoshino S, Hazama S, Oka M, Nagano H. Calreticulin is highly expressed in pancreatic cancer stem-like cells. Cancer Sci. 2016 Nov; 107(11): 1599-1609.

Tanaka S, Hikita H, Tatsumi T, Sakamori R, Nozaki Y, Sakane S, Shiode Y, Nakabori T, Saito Y, Hiramatsu N, Tabata K, Kawabata T, Hamasaki M, Eguchi H, Nagano H, Yoshimori T, Takehara T. Rubicon inhibits autophagy and accelerates hepatocyte apoptosis and lipid accumulation in nonalcoholic fatty liver disease. Hepatology. 2016 Dec; 64(6): 1994-2014.

Ho MC, Hasegawa K, Chen XP, Nagano H, Lee YJ, Chau GY, Zhou J, Wang CC, Choi YR, Poon RT, Kokudo N. Surgery for Intermediate and Advanced Hepatocellular Carcinoma: A Consensus Report from the 5th Asia-Pacific Primary Liver Cancer Expert Meeting (APPLE 2014). Liver Cancer. 2016 Oct; 5(4): 245-256.

Tokumitsu Y, Nagano H. Current HCC Staging Systems: Their Uses and Limitations. In: Carr BI, editor. Hepatocellular Carcinoma: Diagnosis and Treatment. Current Clinical Oncology. 3rd ed. Switzerland: Springer; 2016. p. pp.425-42.

Okubo K, Wada H, Tanaka A, Eguchi H, Hamaguchi M, Tomokuni A, Tomimaru Y, Asaoka T, Hama N, Kawamoto K, Kobayashi S, Marubashi S, Nagano H, Sakaguchi N, Nishikawa H, Doki Y, Mori M, Sakaguchi S. Identification of Novel and Noninvasive Biomarkers of Acute Cellular Rejection After Liver Transplantation by Protein Microarray. Transplant Direct. 2016 Nov 18; 2(12): e118.

Eguchi S, Furukawa H, Uemoto S, Umeshita K, Imamura H, Soyama A, Shimamura T, Isaji S, Ogura Y, Egawa H, Kawachi S, Kasahara M, Nagano H, Ku Y, Ohdan H, Maehara Y, Sato S, Inomata Y. Outcomes of Living Donor Liver Transplantation Alone for Patients on Maintenance Renal Replacement Therapy in Japan: Results of a Nationwide Survey. Transplant Direct. 2016 May; 2(6): e74.

Kitahara M, Hazama S, Tsunedomi R, Takenouchi H, Kanekiyo S, Inoue Y, Nakajima M, Tomochika S, Tokuhisa Y, Iida M, Sakamoto K, Suzuki N, Takeda S, Ueno T, Yamamoto S, Yoshino S, Nagano H. Prediction of the efficacy of immunotherapy by measuring the integrity of cell-free DNA in plasma in colorectal cancer. Cancer Sci. Cancer Sci. 2016 Dec; 107(12): 1825-1829.

Kaibori M, Sakai K, Ishizaki M, Matsushima H, De Velasco MA, Matsui K, Iida H, Kitade H, Kwon AH, Nagano H, Wada H, Haji S, Tsukamoto T, Kanazawa A, Takeda Y, Takemura S, Kubo S, Nishio K. Increased FGF19 copy number is frequently detected in hepatocellular carcinoma with a complete response after sorafenib treatment. Oncotarget. 2016 Aug 2; 7(31): 49091-49098.

Ueda Y, Ikegami T, Soyama A, Akamatsu N, Shinoda M, Ishiyama K, Honda M, Marubashi S, Okajima H, Yoshizumi T, Eguchi S, Kokudo N, Kitagawa Y, Ohdan H, Inomata Y, Nagano H, Shirabe K, Uemoto S, Maehara Y. Simeprevir or telaprevir with peginterferon and ribavirin for recurrent hepatitis C after living donor liver transplantation: A Japanese multicenter experience. Hepatol Res. 2016 Dec; 46(13): 1285-1293.

Usui T, Sakurai M, Enjoji S, Kawasaki H, Umata K, Ohama T, Fujiwara N, Yabe R, Tsuji S, Yamawaki H, Hazama S, Takenouchi H, Nakajima M, Tsunedomi R, Suzuki N, Nagano H, Sato K. Establishment of a Novel Model for Anticancer Drug Resistance in Three-Dimensional Primary Culture of Tumor Microenvironment. Stem Cells Int. 2016;2016:7053872. doi: 10.1155/2016/7053872

2015年

Shimada M, Morine Y, Nagano H, Hatano E, Kaiho T, Miyazaki M, Kono T, Kamiyama T, Morita S, Sakamoto J, Kusano M, Saji S, Kanematsu T, Kitajima M. Effect of TU-100, a traditional Japanese medicine, administered after hepatic resection in patients with liver cancer: a multi-center, phase III trial (JFMC40-1001). Int J Clin Oncol. 2015 Feb; 20(1): 95-104.

Iwagami Y, Eguchi H, Wada H, Tomimaru Y, Hama N, Kawamoto K, Kobayashi S, Mori M, Doki Y, Nagano H. Implications of peritoneal lavage cytology in resectable left-sided pancreatic cancer. Surg Today. 2015 Apr; 45(4): 444-450.

Tomimaru Y, Kobayashi S, Wada H, Hama N, Kawamoto K, Eguchi H, Kira T, Morii E, Doki Y, Mori M, Nagano H. Intrahepatic cholangiocarcinoma in a worker at an offset color proof-printing company: An autopsy case report. Hepatol Res. 2015 Apr; 45(4): 488-493.

Tanida T, Tanemura M, Miyoshi E, Nagano H, Furukawa K, Nonaka Y, Akita H, Hama N, Wada H, Kawamoto K, Kobayashi S, Eguchi H, Mori M, Doki Y. Pancreatic cancer immunotherapy using a tumor lysate vaccine, engineered to express a-gal epitopes, targets pancreatic cancer stem cells. Int J Oncol. 2015 Jan; 46(1): 78-90.

Akita H, Marubashi S, Wada H, Hama N, Kawamoto K, Kobayashi S, Eguchi H, Doki Y, Mori M, Nagano H. Combination therapy with S-1 and interferon-α in hepatocellular carcinoma patients with lung metastasis. Mol Clin Oncol. 2015 Mar; 3(2): 322-328.

Kanai M, Hatano E, Kobayashi S, Fujiwara Y, Marubashi S, Miyamoto A, Shiomi H, Kubo S, Ikuta S, Yanagimoto H, Terajima H, Ikoma H, Sakai D, Kodama Y, Seo S, Morita S, Ajiki T, Nagano H, Ioka T. A multi-institution phase II study of gemcitabine/cisplatin/S-1 (GCS) combination chemotherapy for patients with advanced biliary tract cancer (KHBO 1002). Cancer Chemother Pharmacol. 2015 Feb; 75(2): 293-300.

Hirokawa F, Kubo S, Nagano H, Nakai T, Kaibori M, Hayashi M, Takemura S, Wada H, Nakata Y, Matsui K, Ishizaki M, Uchiyama K. Do patients with small solitary hepatocellular carcinomas without macroscopically vascular invasion require anatomic resection? Propensity score analysis. Surgery. 2015 Jan; 157(1): 27-36.

Furukawa K, Kawamoto K, Eguchi H, Tanemura M, Tanida T, Tomimaru Y, Akita H, Hama N, Wada H, Kobayashi S, Nonaka Y, Takamatsu S, Shinzaki S, Kumada T, Satomura S, Ito T, Serada S, Naka T, Mori M, Doki Y, Miyoshi E, Nagano H. Clinicopathological Significance of Leucine-Rich α2-Glycoprotein-1 in Sera of Patients with Pancreatic Cancer. Pancreas. 2015 Jan; 44(1): 93-98.

Hori M, Okada T, Higashiura K, Sato Y, Chen YW, Kim T, Onishi H, Eguchi H, Nagano H, Umeshita K, Wakasa K, Tomiyama N. Quantitative Imaging: Quantification of Liver Shape on CT Using the Statistical Shape Model to Evaluate Hepatic Fibrosis. Acad Radiol. 2015 Mar; 22(3): 303-309.

Tomimaru Y, Eguchi H, Tatsumi M, Kim T, Hama N, Wada H, Kawamoto K, Kobayashi S, Morii E, Mori M, Doki Y, Nagano H. Clinical utility of 2-[18F] fluoro-2-deoxy-D-glucose positron emission tomography in predicting World Health Organization grade in pancreatic neuroendocrine tumors. Surgery. 2015 Feb; 157(2): 269-276.

Tomimaru Y, Eguchi H, Satoh T, Tomokuni A, Asaoka T, Wada H, Marubashi S, Ogawa K, Takehara T, Mori M, Doki Y, Nagano H. Feasibility of pre-operative chemoradiotherapy with gemcitabine to treat pancreatic cancer in patients with impaired renal function. Jpn J Clin Oncol. 2015 Apr; 45(4): 343-348.

Tomimaru Y, Ito T, Marubashi S, Kawamoto K, Tomokuni A, Asaoka T, Wada H, Eguchi H, Mori M, Doki Y, Nagano H. De novo malignancy after pancreas transplantation in Japan. Transplant Proc. 2015 Apr; 47(3): 742-745.

Fujita Y, Kozawa J, Iwahashi H, Yoneda S, Uno S, Yoshikawa A, Okita K, Eguchi H, Nagano H, Imagawa A, Shimomura I. Increment of serum C-peptide measured by glucagon test closely correlates with human relative beta-cell area. Endocr J. 2015 Apr 30; 62(4): 329-337.

Nakashima S, Kobayashi S, Nagano H, Tomokuni A, Tomimaru Y, Asaoka T, Hama N, Wada H, Kawamoto K, Marubashi S, Eguchi H, Doki Y, Mori M. BRCA/Fanconi anemia pathway implicates chemoresistance to gemcitabine in biliary tract cancer. Cancer Sci. 2015 May; 106(5): 584-591.

Makino Y, Miyazaki M, Shigekawa M, Ezaki H, Sakamori R, Yakushijin T, Ohkawa K, Kato M, Akasaka T, Shinzaki S, Nishida T, Miyake Y, Hama N, Nagano H, Honma K, Morii E, Wakasa K, Hikita H, Tatsumi T, Iijima H, Hiramatsu N, Tsujii M, Takehara T. Solitary fibrous tumor of the liver from development to resection. Intern Med. 2015; 54(7): 765-770.

Mukai R, Tomimaru Y, Nagano H, Eguchi H, Mimori K, Tomokuni A, Asaoka T, Wada H, Kawamoto K, Marubashi S, Doki Y, Mori M. miR-615-3p expression level in bone marrow is associated with tumor recurrence in hepatocellular carcinoma. Mol Clin Oncol. 2015 May; 3(3): 563-571.

Ogawa H, Nagano H, Konno M, Eguchi H, Koseki J, Kawamoto K, Nishida N, Colvin H, Tomokuni A, Tomimaru Y, Hama N, Wada H, Marubashi S, Kobayashi S, Mori M, Doki Y, Ishii H. The combination of the expression of hexokinase 2 and pyruvate kinase M2 is a prognostic marker in patients with pancreatic cancer. Mol Clin Oncol. 2015 May; 3(3): 563-571.

Matsui T, Hori Y, Nagano H, Eguchi H, Marubashi S, Wada H, Wada N, Ikeda JI, Sakamoto M, Morii E. Poorly differentiated hepatocellular carcinoma accompanied by anti-Hu antibody-positive paraneoplastic peripheral neuropathy. Pathol Int. 2015 Jul; 65(7): 388-392.

Noguchi K, Eguchi H, Konno M, Kawamoto K, Nishida N, Koseki J, Wada H, Marubashi S, Nagano H, Doki Y, Mori M, Ishii H. Susceptibility of pancreatic cancer stem cells to reprogramming. Cancer Sci. 2015 Sep; 106(9): 1182-1187.

Ogawa H, Wu X, Kawamoto K, Nishida N, Konno M, Koseki J, Matsui H, Noguchi K, Gotoh N, Yamamoto T, Miyata K, Nishiyama N, Nagano H, Yamamoto H, Obika S, Kataoka K, Doki Y, Mori M, Ishii H. MicroRNAs Induce Epigenetic Reprogramming and Suppress Malignant Phenotypes of Human Colon Cancer Cells. PLoS One. 2015 May 13; 10(5): e0127119.

Tanemura M, Miyoshi E, Nagano H, Eguchi H, Matsunami K, Taniyama K, Hatanaka N, Akamatsu H, Mori M, Doki Y. Cancer immunotherapy for pancreatic cancer utilizing α-gal epitope/natural anti-Gal antibody reaction. World J Gastroenterol. 2015 Oct 28; 21(40): 11396-11410.

Asukai K, Kawamoto K, Eguchi H, Konno M, Nishida N, Koseki J, Noguchi K, Hasegawa S, Ogawa H, Yamada D, Tomimaru Y, Tomokuni A, Asaoka T, Noda T, Wada H, Gotoh K, Marubashi S, Nagano H, Doki Y, Mori M, Ishii H. Prognostic Impact of Peritumoral IL-17-Positive Cells and IL-17 Axis in Patients with Intrahepatic Cholangiocarcinoma. Ann Surg Oncol. 2015 Dec; 22 Suppl 3: 1524-15231.

Beppu T, Wakabayashi G, Hasegawa K, Gotohda N, Mizuguchi T, Takahashi Y, Hirokawa F, Taniai N, Watanabe M, Katou M, Nagano H, Honda G, Baba H, Kokudo N, Konishi M, Hirata K, Yamamoto M, Uchiyama K, Uchida E, Kusachi S, Kubota K, Mori M, Takahashi K, Kikuchi K, Miyata H, Takahara T, Nakamura M, Kaneko H, Yamaue H, Miyazaki M, Takada T.　 Long-term and perioperative outcomes of laparoscopic versus open liver resection for colorectal liver metastases with propensity score matching: a multi-institutional Japanese study. J Hepatobiliary Pancreat Sci. 2015 Oct; 22(10): 711-720.

Sakane M, Tatsumi M, Kim T, Hori M, Onishi H, Nakamoto A, Eguchi H, Nagano H, Wakasa K, Hatazawa J, Tomiyama N. Correlation between apparent diffusion coefficients on diffusion-weighted MRI and standardized uptake value on FDG-PET/CT in pancreatic adenocarcinoma. Acta Radiol. 2015 Sep; 56(9): 1034-1041.

Sakamoto K, Tamesa T, Tokuhisa Y, Matsukuma S, Tokumitsu Y, Maeda Y, Takeda S, Ueno T, Yamamoto S, Yoshino S, Hazama S, Nagano H, Oka M. Perioperative Microbiologic Monitoring of Sputum on Postoperative Day One as a Predictor of Pneumonia after Hepatectomy. J Gastrointest Surg. 2015 Sep; 19(9): 1662-1667.

Fujiwara Y, Kobayashi S, Nagano H, Kanai M, Hatano E, Toyoda M, Ajiki T, Takashima Y, Yoshimura K, Hamada A, Minami H, Ioka T. Pharmacokinetic Study of Adjuvant Gemcitabine Therapy for Biliary Tract Cancer following Major Hepatectomy (KHBO1101). PLoS One. 2015 Dec 3; 10(12): e0143072.

Tomimaru Y, Wada H, Eguchi H, Tomokuni A, Hama N, Kawamoto K, Marubashi S, Umeshita K, Doki Y, Mori M, Wakasa K, Nagano H. Clinical significance of surgical resection of metastatic lymph nodes from hepatocellular carcinoma. Surg Today. Surg Today. 2015 Sep; 45(9): 1112-1120.

Kawaguchi T, Kodama T, Hikita H, Makino Y, Saito Y, Tanaka S, Shimizu S, Sakamori R, Miyagi T, Wada H, Nagano H, Hiramatsu N, Tatsumi T, Takehara T. Synthetic lethal interaction of combined CD26 and Bcl-xL inhibition is a powerful anti-cancer therapy against HCC. Hepatol Res. 2015 Sep; 45(9): 1023-1033.

Hirose K, Matsui T, Nagano H, Eguchi H, Marubashi S, Wada H, Morii E. Atypical glomus tumor arising in the liver: a case report. Diagn Pathol. 2015 Jul 19; 10(1): 112.

Murakami K, Takiguchi S, Miyazaki Y, Kurokawa Y, Yamasaki M, Nagano H, Mori M, Doki Y. Perturbation of acyl ghrelin profile after liver transplantation. J Surg Res. 2015 Dec; 199(2): 450-457.

Wakasugi M, Tori M, Shimizu J, Kim YK, Noda T, Dono K, Takeda Y, Yamamoto T, Oshima S, Morimoto Y, Asaoka T, Eguchi H, Nagano H, Mori M, Doki Y; Hepato-Biliary-Pancreatic Group of the Clinical Study Group of Osaka University. Efficacy of preoperative dexamethasone for postoperative nausea and vomiting after laparoscopic cholecystectomy: A large-scale, multicenter, randomized, double-blind, placebo-controlled trial in Japan. J Hepatobiliary Pancreat Sci. 2015 Nov; 22(11): 802-809.

Sakai K, Tomimaru Y, Eguchi H, Marubashi S, Tomokuni A, Asaoka T, Wada H, Kawamoto K, Umeshita K, Doki Y, Mori M, Nagano H. A resected case of liver metastases from extra-adrenal retroperitoneal paraganglioma with von Recklinghausen’s disease 16 years after the initial surgery. Surg Case Rep. 2015 Dec; 1(1): 84.